Brucellosis is a zoonotic infectious disease caused by bacteria of the genus Brucella. Globally, 1.6–2.1 million human cases of brucellosis are reported annually. Among the countries with the highest reported incidence of brucellosis are: Iran, Kyrgyzstan, Tajikistan, Kazakhstan, Azerbaijan, Turkmenistan, Armenia, and Uzbekistan.

Human infection occurs through contact with infected animals and their biological fluids, as well as through the consumption of animal-derived products (raw milk and insufficiently heat-treated meat). And by the airborne route during occupational exposure. The pathogen enters the human body through mucous membranes or damaged skin. Subsequently, the bacteria are transported by macrophages to lymphoid tissues, spread through the lymphatic system. It may potentially proliferate in multiple organs, causing localized and systemic infections. By persisting within host cells such as macrophages, Brucella spp. employ strategies to evade the host immune response. It results in prolonged infection.

The incubation period of brucellosis usually ranges from 1 to 4 weeks but may extend to several months. Clinical manifestations are characterized by undulating fever, sweating (especially at night), weakness, and enlargement of the lymph nodes, liver, and spleen. In chronic cases, the musculoskeletal, nervous, and cardiovascular systems may also be affected.

Due to the nonspecific nature of its symptoms, the diagnosis of brucellosis is challenging. It requires a comprehensive approach, including the evaluation of clinical findings, epidemiological history, and laboratory test results.

To enable effective and timely diagnosis of brucellosis, Vitrotest Bioreagent has developed and launched into production new high-quality test kit:

Vitrotest® Brucella-IgG, ELISA test kit for the qualitative and semiquantitative determination of igG class antibodies to Brucella in human serum or plasma:

  • TK153 – 96 tests.

We invite you to review detailed information in the updated catalog on our website and place your order by contacting our sales department.